Building Research Capacity in Developmental Origins of CVD

Building   Research Capacity in Developmental Origins of Cardiovascular Diseases   (DO-CVD)

Principal investigators

  • Manuel Ramírez-Zea
  • Dorairaj Prabhakaran
  • Naomi Levitt
  • Reynaldo Martorell
  • Aryeh Stein
  • Caroline Fall
  • Santosh K Bhargava´s
  • Linda Richter
  • Shane Norris
  • Cesar Gomes Victora
  • Linda Adair

Researchers in training

  • Rebecca Kanter

Funding Agency

  • National Heart, Lung and Blood Institute (NHLBI)

Participating   countries

  • Guatemala
  • New Dheli
  • South Africa
  • Brazil
  • Philippines

Participating Institutions

  • Hubert Department of Global Health, Rollins School of Public Health,   Emory University, Atlanta, Georgia.
  • Lifecourse Epidemiology Unit, University of Southampton, Southampton,   United Kingdom.
  • Sunder Lal Jain Hospital, Delhi, India.
  • Human Sciences Research Council, Durban, South Africa.
  • Department of Paeditrics, MRC/WITS Development Pathways for Health   Research Unit, University of the Witwatersrand, Johannesburg, Sout Africa.
  • Postgraduate Program in Epidemiology, Federal University of Pelotas,   Brazil.
  • Department of Nutrition, University of North Carolina at Chapel Hill,   Chapel Hill, North Carolina.

Purpose of the project

  • To strengthen the design and analysis capacity for high quality DO-CVD   research, including inter-generational findings, of interdisciplinary young   researchers at the Centers of Excellence.
  • To promote collaboration among researchers of Center of Excellence and   the COHORTS project, for training and analysis of DO-CVD data.
  • To develop a common standardized set of DO-CVD measurements that may be   collected for future studies in COHORT sites and other cohort birth studies,   particularly to study the relation between nutrition during early life,   chronic inflammation and infection, cardio metabolic risk and socio –economic   results during adulthood.


This project will support a series of technical   meetings and workshops, as well as online activities and communications to   promote interaction between COHORTS and researchers of the Centers of   Excellence. This includes:

  • Two training fellowships for researchers from other Centers of   Excellence granted through competition.
  • A 5-day workshop (New Delhi 2012) to develop common measurements for a   follow-up study in COHORTS sites in order to assess the relation between   early nutrition and infection, chronic inflammation, cardio-metabolic risk   and socio-economic results during adulthood.
  • Periodic online meetings (Skype, Elluminate) between COHORTS   researchers and Centers of Excellence in order to follow up on the data   analysis and writing of scientific papers.

Progress to date

On June, CIIPEC´S General Coordinator, Manuel  Ramírez and Scientific Researcher Rebecca Kanter attended the COHORT´s   initiative coordination meeting and training workshop at Cebu, Philippines.



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